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Highest Quality | For Research Use Only

PTD-DBM

Buy PTD-DBM Peptide France

PTD-DBM, or Protein Transduction Domain – Dishevelled Binding Motif, is a synthetic peptide that holds promise in regenerative medicine and oncology. It modulates the Wnt/β-catenin pathway, affecting cell proliferation, differentiation, and survival. Research suggests by inhibiting Dvl-β-catenin interaction, PTD-DBM impedes the pathway, potentially slowing cancer growth or inducing cell death. Additionally, it influences stem cell differentiation, making it useful for tissue regeneration.

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Potential Benefits of PTD-DBM Peptide

  • Cell Penetrating Ability: According to scientific studies, PTD-DBM peptides, also known as protein transduction domain fused to the mimicking domain of β-catenin, have gained attention due to their cell-penetrating properties. This makes them an effective tool in drug delivery, particularly in targeting intracellular components [1].
  • Wnt/β-Catenin Pathway Activation: The PTD-DBM peptide is known for its role in activating the Wnt/β-catenin signaling pathway, which plays a crucial role in cell proliferation, differentiation, and survival. Research suggests this makes it potentially valuable in regenerative medicine and tissue engineering [2].
  • Bone Regeneration: Research has shown that PTD-DBM can stimulate bone regeneration. In a study published in the Journal of Bone and Mineral Research, PTD-DBM was found to accelerate fracture healing in mice [3].
  • Neuroprotective Effects: Some studies indicate that PTD-DBM may have neuroprotective effects. For instance, a study published in the Journal of Neuroscience showed that PTD-DBM could protect against neuronal death in a Parkinson’s disease model [4].
  • Positive Impact on Hair Growth: Preliminary research suggests that PTD-DBM may enhance hair growth by activating the Wnt/β-catenin pathway, which is known to be involved in hair follicle development and cycling [5].

References

[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4493411/

[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC9831250/

[3] https://pubmed.ncbi.nlm.nih.gov/20641004/

[4] https://pubmed.ncbi.nlm.nih.gov/32050297/

[5] https://www.mdpi.com/2073-4409/12/4/555

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DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://france.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.